Using global amphibian declines as a case study, students will examine how multiple stressors are driving the biodiversity crisis and learn what conservation actions can help mitigate these losses. This lesson includes: 1) a brief PowerPoint on biodiversity and basic amphibian biology and ecology, 2) a card game activity, in which student groups will assess how different natural and anthropogenic stressors influence amphibian survival throughout their complex life cycles, and 3) a reflective Think-Pair-Share discussion on major takeaways from the game.